“Elderberry prevents colds or influenza.”
Elderberry has not been shown to prevent colds or flu, and the only prevention trial found no clear drop in colds.
Taking elderberry is unlikely to keep you from catching a cold or the flu. A product labeled for "immune support" has not been shown to prevent infections.
If your goal is to avoid the flu, get the yearly flu vaccine rather than relying on elderberry.
Safety note: Raw or unripe elderberries and the leaves and stems of the plant contain substances that can cause nausea, vomiting and severe diarrhea; cooking removes them. Elderberry is not a substitute for a flu vaccine.
The only prevention trial, in 312 air travelers, found no clear drop in colds, and no trial has tested whether elderberry prevents flu. Confidence is Limited because that single trial was small for this question and had a high risk of bias.
Elderberry has not been shown to prevent colds or flu, and the only prevention trial found no clear drop in colds. Most other elderberry studies enrolled people who were already sick and looked at symptoms, not whether infections were prevented.
In the prevention trial, Australian air travelers took an elderberry extract or a placebo before and during an overseas trip. 12 of 154 people on elderberry (8%) and 17 of 158 on placebo (11%) caught a cold, a difference that could be due to chance. Colds were shorter in people taking elderberry, but only 29 people caught a cold, and that is a question about shortening colds, not preventing them. A 2021 systematic review rated this evidence low certainty and found no trials of elderberry for preventing flu.
- Wieland LS, Piechotta V, Feinberg T, Ludeman E, Hutton B, Kanji S, Seely D, Garritty C. Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review. BMC Complementary Medicine and Therapies. 2021;21(1):112. DOI: 10.1186/s12906-021-03283-5. PMID: 33827515
- Tiralongo E, Wee SS, Lea RA. Elderberry supplementation reduces cold duration and symptoms in air-travellers: a randomized, double-blind placebo-controlled clinical trial. Nutrients. 2016;8(4):182. DOI: 10.3390/nu8040182. PMID: 27023596. PMCID: PMC4848651
- National Center for Complementary and Integrative Health. Elderberry: Usefulness and Safety. Last updated November 2024
- Centers for Disease Control and Prevention. Treating Flu with Antiviral Drugs. Last updated June 26, 2026